Pharmacology and the Nursing Process by Linda Lane Lilley: Practice Exam

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What is the mechanism of action for ARBs?

  1. Block the conversion of AI to AII

  2. Block the binding of AII to type 1 AII receptors

  3. Increase the breakdown of bradykinins

  4. Promote the secretion of aldosterone

The correct answer is: Block the binding of AII to type 1 AII receptors

Angiotensin II Receptor Blockers (ARBs) are a type of medication that works by blocking the binding of Angiotensin II (AII) to type 1 AII receptors. This leads to a decrease in the constriction of blood vessels, which results in lowered blood pressure. Option A is incorrect as it refers to ACE inhibitors, which are another type of medication. Option C is incorrect as ARBs do not affect the breakdown of bradykinins. Option D is incorrect as ARBs actually work to decrease the secretion of aldosterone, a hormone that causes salt and fluid retention. Therefore, the mechanism of action for ARBs is best described as blocking the binding of AII to type 1 AII receptors.

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