Pharmacology and the Nursing Process by Linda Lane Lilley: Practice Exam

Explanation A: Phenytoin, phenobarbital, and rifampin may interfere with the metabolism of corticosteroids, enhancing their clearance and reducing their effectiveness. This requires careful management to adjust the dosage of corticosteroids. B, C, and D are incorrect because they do not have an effect on corticosteroid levels. Antivirals, antibiotics, antifungals, antimalarials, calcium channel blockers, and diuretics do not alter the metabolism of corticosteroids.